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Drug Study

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting prostaglandin and leukotriene synthesis. It is indicated for short term management of moderate to severe acute post-operative pain and treatment of allergic conjunctivitis and reduction of inflammation following ocular surgery. Common adverse effects include GI upset, headache, rash and diarrhea. It should be used with caution in patients with renal impairment, history of ulcers or asthma.

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Geevine Cansino
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449 views5 pages

Drug Study

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting prostaglandin and leukotriene synthesis. It is indicated for short term management of moderate to severe acute post-operative pain and treatment of allergic conjunctivitis and reduction of inflammation following ocular surgery. Common adverse effects include GI upset, headache, rash and diarrhea. It should be used with caution in patients with renal impairment, history of ulcers or asthma.

Uploaded by

Geevine Cansino
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Generic name: Ketorolac Brand name: Action: Analgesic, anti-inflammatory and antipyretic.

Inhibits prostaglandin synthesis by inhibition of cyclo-oxygenase enzyme. It also inhibits leukotriene synthesis, help stabilize lysosomal membranes and exert anti-bradykinin activity. Indication: Ophthalmic: Treatment of allergic conjunctivitis, and for prophylaxis and reduction of inflammation and associated symptoms following ocular surgery. Solution for injection: Short term management of moderate to severe acute post-operative pain. Contraindication: Active PUD, moderate to severe renal impairment, lactation, dehydration, allergy to ASA or NSAIDs, history of asthma. Adverse effects: Transient stinging and burning on instillation. Inj: GI ulceration, HPN, rash diarrhea, sweating, dizziness. NSG Considerations: Taken with food. Assess for signs of bleeding. Assess patients eyes for redness, swelling, tearing and itching.

Generic name: Brand name: Kefurox-a -lactam type antibiotic. More specifically, it is a second-generation cephalosporin. Action: Interfere with the peptidoglycan synthesis of the bacterial wall by inhibiting the final transpeptidation needed for the cross-links. This effect is bactericidal. Indication: For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections (bacterial infections).

Generic name: Ambroxol (Mucolytic) Brand name: Action: Exerts its clinical effect through the breakdown of disulphide bonds of mucopolysaccharides of the sputum. This allows the liquification of the viscous bronchial mucous through decreasing its viscosity. Indication: Bronchitis, Pneumonia, Otitis media, Sinusitis, Nasopharyngitis, Tracheobronchitis, Bronchiectasis Adverse effects: fatigue, dry mouth, rhinorrhea, constipation, dysuria and contact dermatitis.

Generic name: Phenylpropanolamine Brand name: Neozep Forte Action: Sympathomimetic amine that causes constriction and shrinkage of mucous membranes. Indication: Symptomatic treatment of nasal congestion. It is frequently used in mixed preparations for the relief of cough and colds symptoms. Contraindication: Patients with hyperthyroidism, severe coronary disease, severe hypertension. Adverse effects: Headache, elevated BP, blurred vision, dizziness, anxiety.

Generic name: dextromethorphan Brand name: Strepsils Lozenges Action: Suppressess cough reflex by direct action on the cough center of the medulla. Indication: Unproductive cough, sore throat. Contraindication: Should not be taken for persistent or chronic cough or when coughing is accompanied by excessive secretions, unless directed by a physician. Adverse effects: nausea, drowsiness, or dizziness.

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