DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING

NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Inhibits cell Perioperative Contraindicated in patients CV: phlebitis, Aminoglycosides: Before giving drug
Name: wall prevention hypersensitive to drug or thrombophlebitis May cause ask patient if she is
synthesis other cephalosporin. synergistic activity allergic to penicillin or
cefuroxime promoting against some cephalosporin. Obtain
Brand Name: osmotic 750 mg IV q8 GI: diarrhea, organisms. May specimen for culture
instability Use cautiously in patients anorexia, increase and sensitivity tests
Xorimix usually hypersensitive to penicillin vomiting nephrotoxicity. before giving first
bactericidal because of possibility of Monitor patient’s dose. absorption of
cross-sensitivity with other renal function oral drug is induced.
Pharmalogical beta lactam antibiotics closely.
Hematologic:
Class: hemolytic anemia,
2nd generation thrombocytopenia,
cephalosporin transient
neutropenia,
eosinophilia

Therapeutic
Class:

cephalosporin
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic name: An As an alternative Hypersensitivity to CNS: Absorption of Assessment & Drug

omeprazole antisecretory for patients who omeprazole or to any of its Headache, ketoconazole, Effects:
compound cannot tolerate components dizziness, itraconazole, Lab tests: Monitor
that is a oral therapy in fatigue. ampicillin esters, urinalysis for
Brand name: gastric acid the following GI: Diarrhea, iron salts, and hematuria and
pump conditions: abdominal pain, other drugs whose proteinuria. Periodic
Prilosec inhibitor. benign gastric nausea, mild bioavailability is liver function tests
Suppresses ulcer, duodenal transient dependent on with prolonged use.
Classifications:
gastric acid ulcer, increases in gastric pH may be
gastrointestinal Patient & Family
secretion by gastroesophageal liver function reduced during
agent; proton Education:
inhibiting reflux disease. tests. omeprazole
pump inhibitor Report any changes in
the H+, K+- Urogenital: therapy as with
ATPase Acid aspiration Hematuria, other acid urinary elimination
enzyme prophylaxis proteinuria. secretion inhibitors such as pain or
system [the Skin: Rash. due to decreased discomfort associated
40mg IV OD with urination, or
acid (proton intragastric
H+) pump] activity. blood in urine.
in the Report severe
parietal diarrhea; drug may
cells. need to be
discontinued.

Don’t breast feed

while taking this drug.
 DRUG NAME DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Name: It inhibits Indicated for Contraindicated with Headache, Metronidazole has Before
nucleic acid patients with hypersensitivity to dizziness, ataxia, been reported to Assess pt. Infection
Metronidazole synthesis by Amoebic metronidazole; pregnancy vertigo, potentiate the
(do not use for incoordination, Watch carefully for
disrupting the hepatic abscess, anticoagulant
trichomoniasis in first insomnia, edema because it may
Brand Name: DNA of Intestinal trimester). seizures, effect of warfarin cause sodium
microbial amoebiasis, peripheral and other oral retention
Flagyl, Metric 21, cells. This Trichomoniasis, Use cautiously with CNS neuropathy, coumarin
Noritade, function only Retractory diseases, hepatic disease, fatigue anticoagulants, Assess skin for
Protostat,MetroGel- occurs when trichomoniasis, candidiasis (moniliasis), resulting in a severity areas of local
Vaginal metronidazole Bacterial blood dyscrasias, lactation. Unpleasant prolongation of adverse reactions
metallic taste,
is partially infection prothrombin time.
anorexia, nausea, Record number and
reduced, and caused by vomiting, When character of stools
Classification:
because this anaerobic diarrhea, GI metronidazole is
Antibiotic, reduction microorganism upset, cramps prescribed for Assess pt.’s and
Antibacterial, usually and Pelvic patients on this family’s knowledge
Amebicide, happens only inflammatory Dysuria, type of of drug therapy
in anaerobic disease incontinence, anticoagulant
Antiprotozoal
darkening of the During
cells, it has therapy,
To prevent urine Give drug with meals
relatively prothrombin time to minimize GI
little effect postoperative
Thrombophlebitis and INR should be distress
upon human infection in carefully
(IV); redness,
cells or contaminated burning, dryness, monitored. To treat
aerobic colorectal and skin irritation trichomoniasis, give
bacteria. surgery (topical) drug for 7 days
instead of 2-g single
500mg q8 Severe, dose
disulfiram-like
interaction with Use only after
alcohol, T.vaginalis has been
candidiasis confirmed by wet
(superinfection) smear

Tablets may be
crushed for pt’s. with
difficult swallowing

Do not use aluminium

needles or hubs, color
will turn orange/rust

After
Tell pt. that metallic
taste and dark or red
brown urine may
occur

Instruct pt. to take oral

form with meals to
minimize reactions

Instruct to complete
full course of therapy

Tell pt. not to use

alcohol or drugs that
contain alcohol.

May cause dizziness/

light headedness
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Albumin is Albumin (Human) Contraindicated in patients anaphylactic No interactions Check the albumin
Name: responsible 20% is indicated hypersensitive albumin shock, level from the protein
albumin for 75-80% of in the emergency preparations, any circulatory electrophoresis
the colloid treatment of ingredients in the failure, results. Many clinical
Brand Name: osmotic hypovolemia with formulation or components cardiac problems are the result
Albuminar, pressure of of a serum albumin
or without shock. of the container. failure, and
Albutein, normal deficit.
plasma. For subjects with pulmonary
Buminate,
normal Albumin hypoalbuminemia edema Assess for peripheral
human serum stabilizes who are critically edema in the lower
albumin, circulating ill and/or are extremities when the
Plasbumin blood volume bleeding actively, albumin level is
and is a ALBUMIN decreased. Albumin is
Classification carrier of the major protein
(HUMAN) 20%
blood hormones, compound responsible
enzymes, infusions may be for plasma colloid
products
colloids medicinal indicated.hydrated. osmotic pressure.
products and When blood With a decreased
toxins. volume deficit is albumin level, fluid
the result of seeps out of the blood
Albumin is a hemorrhage, vessels into the tissue
protein with a spaces.
compatible red
total
extravascular blood cells or Assess for urinary
mass of whole blood output. Renal and
approximately should be collagen (lupus)
160 g and an administered as diseases occur with
intravascular quickly as abnormal protein
mass of about possible. fractions. Urine output
120. should be 25mL/h or
20% IV OD 600mL/24 hours.
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Name: Rapid-acting indicated in History of hypersensitivity CV: Postural Some products that Assessment & Drug
potent adults and to furosemide or hypotension, dizziness may interact with Effects
Furosemide sulfonamide pediatric sulfonamides; increasing with excessive this drug include: Observe patients
“loop” diuretic patients for the oliguria, anuria, fluid and diuresis, acute ethacrynic acid, receiving parenteral
and treatment of electrolyte depletion states; hypotensive episodes, lithium. Check the drug carefully; closely
Brand Name: monitor BP and vital
Fumide, antihypertensive edema hepatic coma; pregnancy circulatory collapse. labels on all your
signs. Sudden death
Furomide, with associated with (category C), lactation. medicines (such as from cardiac arrest
Lasix, pharmacologic congestive cough-and-cold has been reported.
effects and uses heart failure, Metabolic: products, diet aids,
Luramide Hypovolemia,
almost identical cirrhosis of the or NSAIDs such as Monitor BP during
to those of liver, and renal dehydration, ibuprofen, periods of diuresis and
Classifications: ethacrynic acid. disease, hyponatremia, naproxen) because through period of
electrolytic hypokalemia, dosage adjustment.
Exact mode of including the they may contain
and water action not nephrotic hypochloremia ingredients that
metabolic alkalosis, Observe older adults
balance agent; clearly defined; syndrome. could increase closely during period
loop diuretic decreases renal hypomagnesemia, your blood of brisk diuresis.
vascular hypocalcemia (tetany), pressure or worsen Sudden alteration in
resistance and hyperglycemia, swelling (edema). fluid and electrolyte
20mg IV OD glycosuria, elevated
may increase balance may
BUN, hyperuricemia;. precipitate significant
renal blood
adverse reactions.
flow. Report symptoms to
GI:Nausea, vomiting, physician.
oral and gastric
burning, anorexia, Lab tests: Obtain
frequent blood count,
diarrhea, constipation, serum and urine
abdominal cramping, electrolytes, CO2,
acute pancreatitis, BUN, blood sugar,
and uric acid values
jaundice.
during first few
Urogenital:Allergic months of therapy and
interstitial nephritis, periodically thereafter.
irreversible renal
failure, urinary Monitor for S&S of
frequency. hypokalemia .
Hematologic:Anemia,
Monitor I&O ratio
leukopenia,
and pattern. Report
thrombocytopenic decrease or unusual
purpura; aplastic increase in output.
anemia, Excessive diuresis can
agranulocytosis (rare). result in dehydration
SpecSenses:Tinnitus, and hypovolemia,
vertigo, feeling of circulatory collapse,
and hypotension.
fullness in ears,
Weigh patient daily
hearing loss (rarely under standard
permanent), blurred conditions.
vision.
Skin:Pruritus, Monitor urine and
urticaria, exfoliative blood glucose &
dermatitis, purpura, HbA1C closely in
diabetics and patients
photosensitivity, with decompensated
porphyria cutanea hepatic cirrhosis.
tarde, necrotizing Drug may cause
angiitis (vasculitis). hyperglycemia.
BodyWhole:Increased
perspiration; Note: Excessive
paresthesias; dehydration is most
activation of SLE, likely to occur in older
adults, those with
muscle spasms,
chronic cardiac
weakness; disease on prolonged
thrombophlebitis, pain salt restriction, or
at IM injection site. those receiving
sympatholytic agents.

Patient & Family

Education
Consult physician
regarding allowable
salt and fluid intake.

Ingestion potassium-
rich foods daily (e.g.,
bananas, oranges,
peaches, dried dates)
to reduce or prevent
potassium depletion.

Learn S&S of
hypokalemia . Report
muscle cramps or
weakness to
physician.

Make position
changes slowly
because high doses of
antihypertensive drugs
taken concurrently
may produce episodes
of dizziness or
imbalance.

Avoid replacing fluid

losses with large
amounts of water.

Avoid prolonged
exposure to direct sun.

Do not breast feed

while taking this drug.
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Given to Dietary Severe renal disorder, Hypersensitivity: Ampicillin esters, Assess patient’s
Name: normalize the supplement abnormal amino acid rare skin iron derivatives, condition before
amino acid, especially for metabolism other than of eruptions ketoronazole: may starting the therapy
Aminoleban carbohydrate, patients with hepatic disorders. cause poor
GI: occasional Be alert to adverse
Brand Name: fats, vitamins liver bioavailability of reaction.
and minerals impairment. nausea and the drugs because
Aminoleban in the plasma Nutritional vomiting they need a low Monitor temperature.
IV support to Others: gastric pH for
patients with optimal If GI reaction occur,
Occasional
chronic liver absorption. Avoid monitor patient
chills, fever and hydration.
Classification: disease headache using it together
Nutritional especially those
products, with hepatic
adult enteral encephalopathy

500cc IV OD
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Name: Reduces Prevention and Galactose and lactose GI: Flatulence, no known Assessment & Drug
blood treatment of intolerance borborygmi, interactions Effects
Lactulose ammonia; portal-systemic belching,
appears to encephalopathy abdominal In children if the
Brand Name:
involve (PSE), cramps, pain, initial dose causes
Cephulac, diarrhea, dosage is
metabolism including stages and distention
reduced immediately.
Chronulac, of lactose to of hepatic (initial dose); Discontinue if
Movelax, Lilac organic precoma and diarrhea diarrhea persists.
acids by coma, and by (excessive dose);
resident prescription for nausea, Promote fluid intake
Classifications: (>=1500–2000 mL/d)
intestinal relief of chronic vomiting, colon
gastrointestinal during drug therapy
bacteria. constipation. accumulation of
agent; for constipation; older
hydrogen gas;
hyperosmotic 30cc OD adults often self-limit
hypernatremia. liquids. Lactulose-
laxative
induced osmotic
changes in the bowel
support intestinal
water loss and
potential
hypernatremia.
Discuss strategy with
physician.

Patient & Family

Education
Laxative action is not
instituted until drug
reaches the colon;
therefore, about 24–48
h is needed.

Do not self-medicate
with another laxative
due to slow onset of
drug action.

Notify physician if
diarrhea (i.e., more
than 2 or 3 soft
stools/d) persists more
than 24–48 h.
Diarrhea is a sign of
over dosage. Dose
adjustment may be
indicated.

Do not breast feed

while taking this drug
without consulting
physician.
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic The inhibition Short-term Aspirin allergy. Peptic Respiratory: It has an increased Don’t forget to assess
Name: of management of ulcer. GI bleed or rhinitis, risk of first the patient before
prostaglandin moderately perforation. As hemoptysis, nephrotoxicity administering this
Ketorolac synthesis by severe, acute prophylactic analgesic dyspnea when use with drug: know the history
competitive pain requiring before any major surgery. other nephrotoxins (e.g. allergies, renal
Brand Name: GI: GI pain, impairment, etc.) and
blocking of the opioid-level Treatment of peri-op pain (e.g.
diarrhea, physical condition of
Toradol enzyme analgesia. in CABG setting. cyclosporine);
vomiting, the patient (reflexes,
cyclooxygenase Advanced renal nausea increased risk of ophthalmologic and
(COX). 30mg IV q8 impairment. Hypovolemia. bleeding when use audiometric
Pharmalogical Cerebrovascular bleeding. CNS: with evaluation,
Class: Hemorrhagic diathesis. dizziness, anticoagulants. orientation, clotting
Incomplete hemostasis. fatigue, times, serum
NSAID insomnia, electrolytes, etc.)
Bleeding disorders or high
headache
risk of bleeding. In case of
Concomitant probenecid, Hematologic: hypersensitivity, be
salicylates, pentoxifylline, neutropenia, sure that emergency
other NSAIDs. Epidural or leukopenia, equipment is
intrathecal inj. Labor & decreased Hgb available.
delivery. or Hct, bone
marrow Drug vials should be
depression protected from light.

Dermatologic: To maintain serum

sweating, dry levels and control pain
mucous effectively, administer
membrane,
pruritus it every six hours.

Report any signs of

itching, swelling in
the ankles, sore throat,
easy bruising, etc.
 DRUG DRUG ACTION INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Elevates the Prevention and Contraindicated in patients Dizziness, Avoid taking this Advise patient to take
Name: serum iron treatment of hypersensitive to iron nausea and medication at the medicine as
concentration iron deficiency preparations. vomiting, same time as prescribed.
Ferrous which then helps anemias. Nasal antacids or
Sulfate tetracycline Caution patient to
to form High or Congestion,
Dietary Contraindicated to patients antibiotics. make position changes
Brand Name: trapped in the supplement for with Severe hypotension.
Dyspnea,
slowly to minimize
reticuloendothelial Hypotension, Consuming coffee,
Feosol cells for storage iron. CHF, MI, orthostatic
tea, or milk may
and eventual Muscle interfere with the hypotension.
Classification: 1tab. BID
conversion to a cramps, absorption of
Iron Instruct patient to
usable form of Flushing ferrous sulfate.
preparation You should talk to avoid concurrent use
iron. of alcohol or OTC
your doctor about
these potential medicine without
interactions. consulting the
physician.

Advise patient to
consult physician if
irregular heartbeat,
dyspnea, swelling of
hands and feet and
hypotension occurs.

Inform patient that

angina attacks may
occur 30 min. after
administration due
reflex tachycardia.

Encourage patient to
comply with
additional intervention
for hypertension like
proper diet, regular
exercise, lifestyle
changes and stress
management.
 DRUG DRUG INDICATION/ CONTRAINDICATIONS ADVERSE DRUG NURSING
NAME ACTION DOSAGE EFFECTS INTERACTIONS CONSIDERATIONS

Generic Water- Prophylaxis and Use of sodium ascorbate in GI: Nausea, Vitamin C in high Assessment & Drug
Name: soluble treatment of patients on sodium vomiting, doses may Effects
vitamin scurvy and as a restriction; use of calcium heartburn, interfere with the
Vitamin C essential for dietary ascorbate in patients diarrhea, or blood-thinning Lab tests: Periodic Hct
(ascorbic synthesis supplement. receiving digitalis. Safety abdominal effects of aspirin, & Hgb, serum
acid) electrolytes.
and during pregnancy (category cramps (high anticoagulants
1tab. OD
Brand Name: maintenance C) or lactation is not doses). such as warfarin or Monitor for S&S of
of collagen established. heparin, and anti- acute hemolytic
Apo- and platelet drugs such anemia, sickle cell
C,Ascorbicap, intercellular Hematologic: as clopidogrel. crisis.
Cebid, Cecon, ground Acute hemolytic Vitamin C may
Cenolate, substance of anemia (patients affect blood sugar Patient & Family
Cemill, C- with deficiency Education
body tissue levels. Caution is
Span, Cetane, cells, blood of G6PD); sickle advised when
cell crisis. High doses of vitamin
Cevalin, Cevi- vessels, using medications C are not
Bid, Ce-Vi- cartilage, that may also recommended during
Sol , Cevita, bones, teeth, CNS: Headache affect blood sugar. pregnancy.
Flavorcee, skin, and or insomnia (high
Redoxon , tendons. Take large doses of
doses). vitamin C in divided
Schiff
amounts because the
Effervescent
body uses only what is
Vitamin C, Urogenital: needed at a particular
Vita-C. Urethritis, time and excretes the
dysuria, rest in urine.
crystalluria,
Classification: hyperoxaluria, or Megadoses can
hyperuricemia interfere with
vitamin (high doses). absorption of vitamin
B12.

Note:Vitamin C
increases the
absorption of iron
when taken at the
same time as iron-rich
foods.

Do not breast feed

while taking this drug
without consulting
physician.