Lesson: Physical Principles
of MRI Image Formation
Kimberly Harn October 3, 2017
Learning Objectives
In this lesson we are are going to go over the basic steps in forming a MRI
image.
How to apply this in a clinical setting?
Why do we need to know these steps?
What do you need to know for the registry?
● MRI does not use Radiation
Basic MRI ● MRI uses Hydrogen atoms as a source
of Magnetism
Physics ● H+ nuclei possess SPIN
What do we know so ● H+ aligns to B0 in scanner
far? ● Precession to Larmor frequency f=y*B0
● Added RF pulses excite the system
● Spins absorb this energy and then
release it
● Different relaxation times for Fat & Water
● Coils collect the energy from RF pulses
How do we ● Magnetic gradients
● Coordinate System
form a MRI ● Phase encoding gradient
image? ● Frequency encoding gradient
● K-space
● Fourier Transform
● Image on computer
Gradients
Alterations in main magnetic field
Generated by coils of wire in bore of magnet
Subtracts or Adds to main magnetic field
Three gradients that allow us to spatially encode the data in an area called K
space
MRI Layout
Gradient Coil location
Induces the Gradient
(magnetic) field around it
MRI layout
Where are gradient coils?
3 Gradient Coils
Named according to axis
Z gradient alters the long axis of the magnet
Y gradient alters the vertical axis of the magnet
X gradient alters the horizontal axis of the magnet
Magnetic isocenter = center point of the axis of all three gradients and the bore
of main magnet
Coordinate System
Typical Superconducting
Magnet
Z green coils
X red coils
Y blue coils
Gradient Coil Locations
Tip
This is typical direction of
gradient coils
Great way to remember
where they are!
FIRST GRADIENT: SLICE SELECTION
Slice Selection
We have to choose a slice or slices that we want Depending on sequence,
to image.
Slice selection can use Z, Y
When we turn on the gradients a specific point
can be selected
or X gradient
These nuclei will have a precessional frequency Axial = Z
We can apply RF with a band of frequency that
matches the slice defined by the gradient Coronal = Y
These slices will be excited and resonance will
occur
Sagittal = X
Slice Selection
Slice Thickness
THICK SLICES:
Shallow slice select gradient
Broad Transmit Bandwidth
THIN SLICES:
Steep slice select gradient
Small Transmit Bandwidth
Example of
gradient slope
Z gradient is turned on, RF pulse
applied. Now we have selected a
slice and thickness of one
particular area. What do we do
next?
Z gradient is turned off- Y
(frequency encoding) and X (phase
encoding) gradients are turned on.
A location within X and Y is
determined.
*This all happens within 8ms - super fast
Phase Encoding
Can be X, Y or Z gradient depending on exam
Definition: the process of locating an MR signal by
altering the phase of spins
Switched on AFTER excitation pulse
It is applied in the Y direction (short axis) to encode
location
Frequency Encoding (readout gradient)
X, Y or Z gradient depending on exam
Remember: LONG axis of body
Definition: locating a signal according to it’s frequency
CREATES A FREQUENCY CHANGE IN EMITTED SIGNAL produces lines or
columns of data
This gradient is switched on DURING collection of signal also called
READOUT
Example
One spot is located by frequency
and phase
Remember: Frequency is the rate
of precession
Phase is the location the proton
is on it’s precession
Slice, Frequency, Phase Encoding Directions
(X,Y, Z) are INTERCHANGEABLE
Just remember
Slice selection is first
Frequency encoding is the LONG axis of anatomy
Phase Encoding is SHORT axis of anatomy
You can change them manually
Each Frequency and Phase
Combination defines its location
within a slice. This data is collected
by the RF receiver coils. When data
of each signal position is collected
they are stored as data points in the
computer called K space.
K space
Not a real space
Is not the Image
A matrix to store data
Data points are spatial frequencies - envision variation in brightness of image
Each spatial frequency contain information about the entire final image
Typically filled line by line 2D acquisition
K space
Edges of K space = High Spatial frequency= resolution/detail
Middle of K space = Contrast
We need ALL parts to create a diagnostic image
Scan time is the time to fill K space
Stored in array processor of computer
K space Mapping
and Filling
Several different ways
Most common: Cartesian
Spiral: Contrast MRA imaging
Radial: Limited MRA Contrast
Zig Zag: Echo Planar Imaging
K space
example
Top Image: All of K space: Good
Image
Middle Image: Only Middle of K
space: Contributes to Contrast of
Image
Last Image: Outer edges of K
space: Contributes to Resolution
and detail
Fourier Transform
Shape can be reconstructed from
periodic signals
Using Fourier Transform
Fast Fourier Transform: mathematical process to produce an image from
acquired data points.
Turns K space into Pixels. Each pixel is allocated a color on the grayscale
corresponding to frequency which equals a location.
Each data point contains info from the whole slice
Matrix, Voxel, Pixel
Matrix: determined by the
number of frequency and phase
encoding steps in each direction
Voxel: Volume of tissue
determined by slice thickness
represented in 3D
Pixel: the face of the Voxel is the
Pixel 2D
Slice
Patient in Fourier
selection/ K space 2 D image
MRI Transform
Gradients
An Analogy:
Imagine Driving A Car
1. Ignition -Turn on the Engine/Patient in magnet
2. Accelerate - Apply RF pulses
3. Steering - with Gradients
4. Final Destination - Image
How do we use this info In clinical...
Setting up and Planning sequences:
REMEMBER: Use 2 planes to plan Use Localizer Images Doublecheck!
Axial sequence: Plan slices on a Coronal and Sagittal image
Coronal sequence: Plan slices on an Axial and Sagittal image
Sagittal Image: Plan slices on a Coronal and Axial image
Why?
It is important to know this information because it will directly correlate to slice
planning at your workstation
It will enable you to obtain quality, diagnostic images in the shortest amount of
time
You will understand how to fix mistakes or poor images
You will feel confident to be creative when you have to think “outside the box”
This will be YOU a MR star!
Planning Example
MRI Imaging Process: Physical Principles of
Image Formation
Slice Selection: A slice is selected from the body
Frequency encoding and Phase Encoding: Magnetic Field gradient is applied to the slice in the Phase
encoding and Frequency encoding directions
–only the protons within the slice to oscillate between their two energy states (spin states)
At the same time radio frequency pulses are applied to the slice with a bandwidth capable of exciting
all resonances simultaneously
The emitted energy is measured by a radio frequency receiver and converted into a K space in the
array processor of the computer
MRI Imaging Process cont...
Fourier Transform: Mathematical equation that translates the K space data into grayscale pixels that
can be viewed as an 2D accurate image of the physical slice
For the ARRT registry...
Spatial Localization
a. X,Y,Z coordinate system
b. Physical gradient
c. Slice select gradient
d. Phase encoding gradient
e. Frequency (readout) gradient
f. K-space (raw data) including mapping and filling
g. Fast Fourier Transform
Common Questions
Why does the MRI scanner make so much Can the phase encoding gradient be applied the
noise? same time as the frequency encoding gradient?
Difference between CT and MRI images? Why is it called “K space?”
How is slice thickness increased? Why does MRI take so long?
How many MRI signal measurement are needed What is spatial resolution?
to form an image?
Objectives for Next Class
Critical Thinking Assignment:
● Read Chapter Four
● Phase encoding and frequency encoding
(1.)If the Fourier Transform equation was not
diagrams
discovered would we still be able to form an
● Data Manipulation
image from MRI? Why or why not?
● Post processing
(2.) Find another area where Fourier Transform
plays an integral role and give a synopsis.
This will require a little research. Minimum 300
words. One APA resource.
Post to Discussion Board Due Sunday 11:59pm
Extra Learning Resources
MRI Sounds: MRI overview video:
https://youtu.be/BFDvIC8AtfQ https://youtu.be/0Puo4DJTzAM
Interesting Study: K space quick video
https://www.itnonline.com/content/residual-ech https://youtu.be/8K0b3MVEkJc
o-ancient-humans-may-hold-clues-mental-disord
ers