THIRD PROFESSIONAL

Theory
Paper 1 Pathology 50
Paper 2 Pharmacology and Therapeutics-II 100
Paper 3 Pharmacognosy-II (Advanced) 100
Pharmacy Practice-II (Dispensing, Community, Social &
Paper 4
Administrative Pharmacy) 100
Paper 5 Pharmaceutical Chemistry-III (Pharmaceutical Analysis) 100
Paper 6 Pharmacy Practice -III (Computer and its Applications in Pharmacy) 50
Practical
Paper 7 Pathology 50
Paper 8 Pharmacology and Therapeutics-II 100
Paper 9 Pharmacognosy-II (Advanced) 100
Paper Pharmacy Practice-II (Dispensing, Community and Social &
10 Administrative Pharmacy) 100
Paper
Pharmaceutical Chemistry-III (Pharmaceutical Analysis)
11 100
Paper
Pharmacy Practice -III (Computer and its Applications in Pharmacy)
12 50
Total Marks: 1000

PATHOLOGY (Theory)

Paper 1 Mar ks 50

Course Objective:

The subject of pathology shall enable the students regarding--

(i) awareness of different diseases;
(ii) condition of diseases;
(iii) physiological variation in different diseases; and
(iv) hormonal changes in different diseases.
1. SCOPE OF PATHOLOGY & CONCEPT OF DISEASES:
2. DEFINITION AND TERMINOLOGY: Ischemia, Hypoxia, Necrosis, Infarction,
Atrophy, Hypertrophy, Hyperplasia, Metaplasia, Aplasia, Anaplasia.
3. RESPONSE OF BODY TO INJURY AND INFECTION: Acute and
Chronic inflammation, Immunity, Allergy, Hyper Sensitivity.
4. SPECIFIC DISEASES: Ulcer (Peptic, Duodenal), Hypertension, Leukemia or Blood
Cancer (Malignant Carcinoma, Sarcoma & Lymphomas), Diagnosis and treatment of
Cancer in general, fate, survival and prognosis with tumors.

PATHOLOGY (Practical)

Paper 7 Mar ks 50

Study of Pathological Slides of various Pathological Conditions: Acute inflammation,

Chronic inflammation, Chronic specific inflammation, Different types of
Degeneration, Thrombosis, Emboli sm, Infarction, Necrosis, Gangrene, Hyperplasia,
Metaplasia, Pigmentation, Calcification, CVC, Papilloma, Adenoma, Chondroma,
Fibroma, Leomyoma, Neofibroma, Sq uamous Cell Carcinoma, Basal Cell Carcinoma,
Transitional Cell Carcinoma, Adenocarcinoma, Fibrocarcinoma, Rhadomyo sarcoma,
Leomyo sarcoma, Lymphosarcoma, Liposarcoma, Reticular Cell Sarcoma, Hodgkins
disease, Breast Carcinoma, Osteogenic Sarcoma, Osteoclastoma, Hapatitis, Diabetes.

Examination of different body fluids in various Pathological Conditions: Urine

Complete Examination, Stool Examination, Blood Complete Examination, Semen
Examination, Cerebrospinal Fluid Examination, Pericardial Fluid Examination, Pleural
Fluid Examination, Ascitic Fluid Examination, Blood Sugar, Blood Urea, Blood
Cholesterol etc.

Tests for various specimens of clinical i mportance: Techniques of Clinical Blood

 Examination for various disases, Gastric Analysis, Tests for liver function, Renal function
test, Tests for endocrine abnormalities, Biopsies and cytologic techniques.

SUGGESTED READINGS:

1. Dipiro J, Talbert RL, Yee G, Matzke G, Wells B, Michael PL.

Pharmacotherapy: A Pathophysiologic Approach. 8th Ed. McGraw Hill; 2011.

2. Greene RJ, Harris ND. Pathology and therapeutics for pharmacists. 3rd Ed.
Pharmaceutical press; 2008.

3. Kumar V, Cotran RS, Robbins SL. Robbin’s Basic Pathology. 8th Ed. W. B.
Saunders Publishers; 2007.

4. Macfarlane PS, Reid R, Collander R. Pathology Illustrated . 5th Ed. Churchill

Livingstone; 2000.

5. Walter GB. Walters and Israel General Pathology. 7th Ed. Churchill Livingstone;
1996.

PHARMACOLOGY AND THERAPEUTICS-II (Theory)

Paper 2 Mar ks 100

Course Objective:

The main objective of this course is to introduce the action of drugs in biological systems. It
will include both pharmacokinetics and pharmacodynamics studies.

1. DRUGS ACTING ON CENTRAL NERVOUS SYSTEM :

a. Sedatives & Hypnotic

b. Anxiolytics, antidepressants and anti -manic drugs
 c. Antiepileptics
d. Antiparkinsonian and drug used in other neurodegenerative diseases.
e. Antips ychotics
f. Opioid analgesics
g. Therapeutic gases (Oxygen, Carbon -dioxide, Nitric oxide and Helium.
h. Cerebral Stimulants, Medullary stimulants, Spinal Cord Stimulant
i. Anesthetics: General and local

2. NON-STEROIDAL ANTI-INFLAMMATORY DRUGS: Disease modifying

antirheumatic drugs, non- opioid analgesics and drugs used in the treatment of gout.

3. CHEMOTHERAPY

 Basic principles of chemotherapy

 Antibacterials (Folate antagonists :sulphonamides, Cell wall synthesis inhibitors;

Penicillin, Cephalosporins, Carbapenam, Monobactam, Protein synthesis inhibitors;
Aminoglycosides, Tetracyclines, Chloramphenicol, Macrolides, Nucleic acid synthesis
inhibitors; Quinolones and miscellaneous Antibiotics), Anti-mycobacterial drugs, Urinary
tract antiseptics,

 Anti-fungals

 Anti-virals

 Anti-protozoals: anti-malarias, anti-amebiasis, anthelmintics and anti-leishmanials.

 Anti-neoplastic drugs

4. IMMUNOPHARMACOLOGY: Pharmacology of immune-suppressants and stimulants

5. TOXICOLOGY

a. Pollution and its types (water, air, food)

b. Poison and principle of treatment of poisoning.

 c. Poisoning (Sign & symptom and treatment): Ethanol, Barbiturates, Digitalis,
Salicylates, Strychnine, Narcotics, Nicotine, Paracetamol, Benzodiazepines and
Organophosphorous compounds.

d. Chelating agents and their role in poisoning: Dimercaprol, Calcium disodium

Edetate (Calcium EDTA), Pencillamine and Defroxamine.

NOTE:

1. Only an introduction will be given of the banned and obsolete drug products.
2. While dealing with Pharmacology stress should be laid to the group actions of related
drugs and only important differences should be discussed of the individual drugs
placed in same group.
3. Newly introduced drugs should be included in the syllabus while drugs with no clinical
and therapeutic values ought to be excluded from syllabus at any time.
4. The prototype drugs in each group from the latest edition of the recommended books.

PHARMACOLOGY AND THERAPEUTICS-II (Practical)

Paper 8 Mar ks 100

NOTE: Practical of the subject shall be designed from time to time on the basis of the above
mentioned theoretical topics and availability of the facilities, e.g.

 To study the convulsant effects of strychnine and picrotoxin in frogs and to determine the
site of action.

 To identify the unknown (convulsant) drug and determine its site of action.

 To study the effects of Adrenaline on Human Eyes.

 To study the effects of Pilocarpine on Human Eyes.

  To study the effect of Homatropine on Human Eyes.

 To identify and observe the effects of unknown drugs on Human Eyes.

 To study the effects of local anaesthetic drugs on human and the nerve plexus of frog.

 To identify and differentiate the effects of unknown drug on human and the nerve plexus
of frog.

 To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and
competitive pharmacological antagonism by Neuromuscular blocking agent e.g.
Gallamine.

 To identify the unknown drug by performing pharmacological competitive antagonism on

Rectus abdominus muscle of Frog.

 To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.

 To identify the unknown anticoagulant drug using Rabbits.

 To demonstrate the Graded Dose-Response curve of Acetylcholine on Rabbit intestine.

 To identify unknown concentration of Acetycholine from Graded Dose Response curves.

 To demonstrate the general anesthetic effect on rabbits.

 To demonstrate the effect of sedatives and hypnotics on rabbits.

 To demonstrate the anti-nociceptive (analgesic) effect on mice.

 To demonstrate antidepressant effect in rats (forced swimming test, tail suspension test
Yohimbin lethality test).

(Note: A minimum of 20 practicals will be conducted ).

SUGGESTED READINGS:

1. Brunton L, Lazo J, Parker K. Goodman & Gilman’s Pharmacological Basis of

 Therapeutics . 11th Ed. McGraw Hill Book Company; 2005.
2. Chang HM, But PPH, Yao SC, Wang LL, Yeung SCS. Pharmacology and

applications of Chinese Materia Medica. 3rd Ed. World Scientific Pub Co Inc; 2000.

3. Ebadi M. Pharmacology. 3rd Ed. Little Brown & Company; 1996.

4. Harvey RA, Champe PC. Lippincott's Illustrated Reviews: Pharmacology. 4th Ed.
Lippincott William & Wilkins; 2008.

5. Humphrey P. Rang & Dale's Pharmacology. 6th Ed. Churchil Livingstone; 2007.

6. Katzung BG, Masters SB, Trevor AJ. Basic & Clinical Pharmacology. 11th Ed.
McGraw Hill; 2009.
7. Koda KMA, Young LY, Kradjan WA, Guglielmo BJ, Alldredge BK, Corelli RL.

Applied therapeutics: the clinical use of drugs. 9th Ed. Lippincott Williams & Wilkins;
2008.

8. Laurence DR. Clinical Pharmacology. 8th Ed. ELBS Publishers; 1998.

9. Ritter JM, Levis LD. A Text Book of Clinical Pharmacology. 5th Ed. Ox ford
University Press; 2008.

10. Satorkar RS, Bhandarkar SD. Pharmacology and Pharmacotherapeutics . 19th Ed.
Bomby: Popular Prakashan; 1998.

11. Tripathi JD. Essentials of Medical Pharmacology. 6th Ed. Jaypee Brothers; 2008.
12. Wecker L, Crespo L, Dunaway G, Faingold C, Watts S. Brody's Human

Pharmacology. 5th Ed. Mosby Inc; 2009.

PHARMACOGNOSY-II (ADVANCED) (Theory)

Paper 3 __ Mar ks 100

Course Objective:
The main objective of this course work is to enhance the knowledge of plants having medicinal
activity.

1. SEPARATION AND ISOLATION OF PLANT CONSTITUENTS: Introduction and use

of spectroscopic and chromatographic techniques for the identification of natural products.

Description and interpretation of ultraviolet, infrared, mass, nuclear magnetic resonance (1H-

NMR and 13C-NMR) and other advance techniques to elucidate the structure of natural products.

2. CARBOHYDRATES AND RELATED COMPOUNDS: Introduction and classification of

carbohydrates, sugars as adjuvant in drugs, role of impurities in sugar substances.

a. Sucrose and Sucrose containing drugs: Sucrose, Dextrose, Liquid glucose, Fructose,
Lactose, Xylose, Caramel, Starch, Inulin, Dextrine etc.
b. Cellulose and Cellulose Derivatives: Powdered cellulose, microcrystalline cellulose,
Methyl cellulose, Sodium Carboxy-methyl cellulose.
c. Gums and Mucilage: Tragacanth, Acacia, Sodium Alginate, Agar, Pectin.

3. ALKALOIDS: Introduction, Properties, Classification, Function of alkaloids in plants,

Method s of extraction and identification tests.

(a) P yridine Piperidine Alkaloids: Areca nut, Lobelia.

(b) Tropane Alkaloids: Belladonna, Hyoscyamus, Stramonium.

(c) Quinoline Alkaloids: Cinchona.

(d) Isoquinoline Alkaloids: Ipecacuanha, Opium.

(e) Indole alkaloids: Rauwolfia, Catharanthus, Nux vomica, P hysostigma, Ergot.

(f) Imidazole alkaloids: Pilocarpus.

(g) Steroidal alkaloids: Veratrum.

 (h) Alkaloidal amines: Ephedra, Colchicum.

(i) Purine Bases: Tea, Coffee.

4. GLYCOSIDES: Introduction, classification, chemistry, extraction, isolation and medicinal

uses of:

a) (Cardioactive glycosides: Digitalis, Strophanthus and white squill.

b) Anthraquinone glycosides: Cascara, Aloe, Rhubarb, Cochineal and Senna.

c) Saponin glycosides: Glycyrrhiza, Sarsaparilla.

d) Cyanophore glycosides: Wild cherry.

e) Isothiocyanate glycosides: Black mustard.

f) Lactone glycosides: Cantharide

g) Aldehyde glycosides: Vanilla.

h) Miscellaneous glycosides: Gentian, Quassia, Dioscorea

5. PLANT STEROIDS: Introduction, extraction, isolation, nomenclature, sources and uses of

bile acids, plant sterols, steroidal sapogenins, steroid hormones, withanolides and ecdysons.

6. LIPIDS: Introduction, classification, source, active constituents and pharmacological uses

of:

a. Fixed Oils: Castor oil, Cotton seed oil, olive oil, Peanut oil, Sun flower oil, Corn oil,
Coconut oil, Almond oil, Lin seed oil, Mustard oil, Sesame oil and S oybean oil.
 b. Fats and Related Compounds: Theobroma oil and Lanolin. (c) Waxes: Bees wax,
carnauba wax, spermaceti and Jojoba oil.

7. VOLATILE OILS (ESSENTIAL OILS): Introduction, significance, sources, active

constituents, methods of obtaining volatile oils, chemistry and classification of:

a. Hydrocarbon volatile oils: Cubeb and Turpentine oil.

b. Alcoholic volatile oil s: Peppermint, Coriander and Cardamom.
c. Aldehydic volatile oils: Bitter orange peel, Sweet orange peel, Lemon
Cinnamon and Bitter almond oil
d. Ketonic volatile oils: Camphor, Spearmint, Caraway, Buchu
e. Phenolic volatile oils: Clove, Thyme.
f. Phenolic ether volatile oils: Fennel, Anise, Myristica. (g) Oxide volatile oils:
Eucalyptus, Chenopodium.
g. Ester volatile oils: Rosemary.
h. Miscellaneous volatile oils: Allium, Anethum.

8. RESINS AND OLEORESINS: Introduction, classification, active constituents and

pharmacological uses of jalap, turpentine, asafoetida, benzoin, rosin, cannabis, podophyllum,
ipomea, myrrh, and balsam.

9. TANNINS: Introduction, classification, biosynthesis, extraction, identification, occurrence in

plants, role in plant life and chemical study of tannins in Kino, Myrobalan, Catechu, Nutgall,
Castanea and krameria.

10. NATURAL TOXICANTS:

a. General Introduction to Plant Toxicology: Definition, classification and chemical

nature of plant toxins. Plant toxicities in humans and animals
b. Higher Plant Toxins: Essential oils: Terpene (cineol, pine oil), Phenyl propane (apiol,
safrole, myristicin), Monoterpene (thujone, menthafuran) Plant acids (oxalic acid,
amino acid, resin acid), Glycosides (cardiotonic, cyanogenic), Alkaloids (imidazole,
pyrrolizidine, tropane).
 c. Lower Plant Toxins: Bacterial toxins (Staphylococcus aureus, Clostridium
botulinum), Algal toxins (Microcystis aeruginosa, Cyanobecteria, Gonyaulax
cantenella).
d. Mycotoxins: Fungal toxins (Aspergillus spp., Claviceps purpurea), Mushrooms
(Amanita spp.).
e. Study of Toxins, their Prevention and Control Methods: Description, pharmacognostic
features, pharmacological actions, chemical constituents, treatment, side -effects,
contra-indications, warnings, prevention and control methods of Abrus precatorius,
Papaver somniferum, Eucalyptus spp., Nicotiana tabaccum, Cannabis sativa, Digitalis
purpurea, Datura stramonium etc. poisoning.

11. AN INTRODUCTION TO NUTRACEUTICALS AND COSMECEUTICALS:

12. TUMOUR INHIBITORS FROM PLANTS: Introduction of anticancer agents of natural

origin, as Catharanthus roseus, Colchicum autumnale, Podophyllum peltatum, rifamycin
antibiotics, macrolide antibiotics, anti-AIDS agents and immunostimulants.

13. INTRODUCTION TO CLINICAL PHARMACOGNOSY: General introduction and

historical background of clinical Pharmacognos y. Study of treatment by herbal medicines.

14. CLINICAL USE OF HERBS & HERBAL MEDICINE:

Diabetes: Gymnema sylvestre, Melia azadirchta, Momordica charantia,

Syzygium jambulana.

Cardiac diseases: Digitalis spp., Convallaria majalis, Urgenia indica, Allium

sativum, Punica granatum.

Hepatitis: Berberis vulgaris, Picrorhiza kurroa, Lawsonia in.

Respiratory diseases: Ficus religosa, Adhatoda vasica

Skin diseases: Aloe vera, Angelica archangelica, Mentha piperita, Citrus spp.,
Commiphora mukul
CNS disorders: Strychnos nux-vomica, Datura stramonium, Cannabis sativa,
Papaver somniferum, Atropa belladonna

Musculo-skeletal disorders: Nigella sativa, Phycotis ajowan, Trigonella foenum-graecum,

Zingiber officinale.

Renal disorders: Cucumis melo, Berberis vulgaris, Zea mays, Tribulus terrestris

Reproductive disorders: Saraca indica, Ruta graveolens, Nigella sativa, Glycyrrhiza

glabra, Claviceps purpurea, Myristica fragrance.

G.I.T. disorders: Foeniculum vulgare, Ferula foetida, Cuminum cyminum, Aegle

marmelos, Prunus domestica.

PHARMACOGNOSY-II (ADVANCED) (Practical)

Paper 9 Mar ks 100

NOTE: Practical of the subject shall be designed from time to time on the basis of the above
mentioned theoretical topics and availability of the facilities, e.g. Extraction of the active
constituents of crude drugs and chemical tests for thei r identi fication. Isolation and separation
of active constituents of crude drugs by paper and thin layer chromatography.

Also include the following experiments;

 Determination of Iodine value; Saponification value and unsaponifiable matter; ester

value; Acid value.
 Chemical tests for Acacia, Tragacanth, Agar, Starch, Lipids, (Castor oil, Sesame oil,
Shark liver oil, Bees wax), Gelatin.

(Note: A minimum of 20 practicals will be conducted ).

SUGGESTED READINGS:
 1. Anonymous. Monographs of Unani Medicine. Hamdard Foundation Pakistan; 2003.

2. Baker BM, Bender DA. Vitamins in Medicine. 12th Ed. Academic Press; 1982.
3. Brain KR, Turner TD. The Practical Evaluation of Phytopharmaceuticals.

1st Ed. Scientechnica Publishers; 1975.

4. Braun L, Cohen M. Herbs and Natural Supplements: An Evidence Based Guide.

3rd Ed. London: Elsevier Mosby; 2010.

5. Chauhan P. Ayurvedic Pharmacognosy. 1st Ed. Sonali Publications; 2007.

6. Cutler SJ, Cutler HG. Biologically Active Natural Products: Pharmaceuticals. 1st
Ed. CRC Press Publisher; 1999.

PHARMACY PRACTICE -II (DISPENSING, COMMUNITY, SOCIAL &

ADMNISTRATIVE PHARMACY) (Theory)

Paper 4 Marks 40+60

Course Objective:

The main objective of this course is to improve dispensing services with special reference to
community health.

PART A: (DISPENSING): (40 MARKS)

1. BASIC PRINCIPLES OF COMPOUNDING AND DISPENSING

INCLUDING: Fundamental operations in Compounding, Containers and closures for
Dispensed Products, Prescription-Handling (Parts of Prescription, Filling, Interpretation,
Pricing) and Labelling of Dispensed Medication.
2. EXTEMPORANEOUS DISPENSING : Solutions, Suspensions, Emulsions,
Creams, Ointments, Pastes and gels, Suppositories and pessaries, Powders and granules
and Oral unit dosage form.
3. PHARMACEUTICAL INCOMPATIBILITIES: Types of Incompatibilities,
manifestations, Correction and Prevention with reference to typical examples.
PART B : (COMMUNITY, SOCIAL & ADMINISTRATIVE PHARMACY): (60
MARKS)

1. DEFINITIONS AND BACKGROUND:

2. PUBLIC HEALTH AND COMMUNITY PHARMACY: Epidemiology & its
Control, Epidemiological methodology with a focus on specific disease states,
Pharmacoepidemiology (including Drug Utilization Review). Preventive Health (EPI &
CDC), Family Planning and Health Policy.
3. MEDICAL COMPLICATION OF DRUG TAKING: General and Socio -
economic Aspects.
4. PATIENT E DUCATION AND COUNSELLING :
5. CONTROL OF DRUG ABUSE AND MISUSE :
6. ROLE OF PHARMACIST: As Public Health Educator in the Community for
Drug Monitoring and Drug Information.
7. HEALTH SYSTEM RESEARCH: Knowledge skills of research methods,
epidemiologic study design, experimental study design, Pre - and post-marketing
surveys, Application of various statistical procedures in P harmacy and Medical
Research, causality assessment as well as the sensitivity and specificity tests in
pharmacy practice.
8. PHARMACOECONOMICS: Pharmacoeconomic modelling and interpretation.
9. ALTERNATIVE THERAPIES: Background, philosophy and u se of
complementary and alternative therapies including herbal medicines, homoeopathy,
acupuncture, acupressure, Bach Flower remedies, aromatherapy and reflexology.
10. PHARMACY LAYOUT DESIGN: Objectives of Layout Design, Types of
Community Pharmacies (Pharmaceutical Centre, Prescription-oriented Pharmacies,
Traditional Pharmacies and The Super Drug Store), Consumer goods and
purchases, Classes of Layout designs, Principles and characteristics of Layout Design
and Traffic Flow analysis.
 PHARMACY PRACTICE -II (DISPENSING, COMMUNITY, SOCIAL &
ADMNISTRATIVE PHARMACY (Practical)

Paper 10 Mar ks 100

NOTE: Practical of the subject shall be designed from time to time on the basis of the above
mentioned theoretical topics and availability of the facilities e.g. Practical introduction to
prescription -handling, interpretation, filling and labelling.

Mixtures: Dispensing of simple mixtures containing soluble substances only, mixtures

containing diffusible substances, in -diffusible substances and mixtures forming precipitate.

Powders: Dispensing of simple powders, compound powders and effervescent powders for
external use.

Incompatibility: Practical Importance of Incompatibilities

Ointments And Creams: Dispensing of iodine and methyl salicylate ointment. Dispensing of
cold cream and vanishing creams.

Cosmetics: Lipstick, talcum powder, after shave lotion, shaving cream. (Note: A minimum of
20 practicals will be conducted ).

Health Science Research Project: In the area of health care system, community pharmacy.
Establishment of DIC, PCC,

SUGGESTED READINGS:

1. Armstrong NA, James KC. Understanding experimental design and

interpretation in pharmaceutics. 1st Ed. Taylor & Francis Publishers; 1990.

2. Gennaro AR. Remington: The science and practice of pharmacy. 21st Ed. Lippincott
Williams & Wilkins; 2011.
3. Marriott JF, Wilson KA, Langley CA, Belcher D. Pharmaceutical compounding

and dispensing. 2nd Ed. Pharmaceutical Press; 2010.

4. Cooper JW, Gunn C, Carter SJ. Cooper and Gun’s Dispensing for Pharmaceutical

Students. 12th Ed. CBS Publishers & Distributors; 2008.

5. Lund W. The Pharmaceutical Codex: Principles and practice of pharmaceutics. 16th

Ed. Co CBS Publishers; 2009.

6. Mehta DK. British national formulary (BNF). 54th Ed. Pharmaceutical Press; 2007.

7. Rowe RC. Handbook of pharmaceutical excipients. 6th Ed. Pharmaceutical press; 2009.

8. Winfield AJ, Rees J, Smith I. Pharmaceutical Practice. 4th Ed. Churchill Livingstone;
2009.
9. Allen LV, Popovich NG, Ansel HC. Ansel's Pharmaceutical Dosage Forms

and Drug Delivery Systems. 9th Ed. Lippincott Williams & Wilkins; 2010.
10. Armstrong NA, James KC. Understanding Experimental Design and

Interpretation in Pharmaceutics. 1st Ed. Taylor & Francis publishers; 1990.

11. Cooper JW, Gunn C, Carter SJ. Cooper and Gun’s Dispensing for Pharmaceutical

Students. 12th Ed. CBS Publishers & Distributors; 2008.

12. Desselle SP, Zgarrick DP. Pharmacy Management: Essentials for all Practice Settings.

2nd Ed. McGraw Hill; 2008.

13. Gennaro AR. Remington: The science and Practice of Pharmacy. 21st Ed. Lippincott
Williams & Wilkins; 2011.

14. Lund W. The pharmaceutical Codex: Principles and Practice of Pharmaceutics. 16th
Ed. Co. CBS Publishers; 2009.
15. Marriott JF, Wilson KA, Langley CA, Belcher D. Pharmaceutical Compounding

and Dispensing. 2nd Ed. Pharmaceutical Press; 2010.

16. Martindale W, Westcoot W. Martindale: The Complete Drug Reference. 1st

Ed. Pharmaceutical Press; 2008.

17. Mehta DK. British National Formulary (BNF). 54th Ed. Pharmaceutical Press; 2007.
18. O'Donohue WT, Levensky ER. Promoting Treatment Adherence: A practical

handbook for health care providers. 1st Ed. Sage Publications; 2006.

19. Osol A. Remington’s Pharmaceutical Sciences. 17th Ed. Mack Publishing Company;
2001. 12. Spivey RN, Wertheimer AI, Donald RT. International pharmaceutical
services: The Drug

20. Industry and Pharmacy Practice in Twenty Three Major Countries of the World. 1 st Ed.
Informa Healthcare; 1996.
21. Robertson R. Management of Drug Users in the Community: A practical Handbook.

1 st Ed. Hodder Arnold Publishers; 1998.

22. Rowe RC. Handbook of Pharmaceutical Excipients. 6th Ed. Pharmaceutical Press; 2009.

15. Saha GB. Fundamentals of Nuclear Pharmacy. 6th Ed. Springer Verlag; 2010.
23. Desselle SP, Zgarrick DP. Pharmacy management: Essentials for all practice settings.

2nd Ed. McGraw Hill; 2008.

24. Spivey RN, Wertheimer AI, Donald RT. International Pharmaceutical Services: The
Drug Industry and Pharmacy Practice in Twenty Three Major Countries of the

World. 1st Ed. Informa Healthcare; 1996.

25. Martindale W, Westcoot W. Martindale: The Extra Pharmacopeia. 31st Ed.

Pharmaceutical Press; 2008.
26. O'Donohue WT , Levensky ER. Promoting treatment adherence: A practical

handbook for health care providers. 1st Ed. Sage Publications; 2006.

27. Winfield AJ, Rees J, Smith I. Pharmaceutical Practice. 4th Ed. Churchill Livingstone;
2009.

PHARMACEUTICAL CHEMISTRY-III (PHARMACEUTICAL ANALYSIS)

(Theory)
Paper 5 Mar ks 100
Course Objective:

In this subject all topics of analytical method will be taught with special reference to their
Pharmaceutical Applications.

1. SPECTROSCOPIC METHODS: Theory, Inst rumentation and Pharmaceutical

applications of the following Spectroscopic Methods:
a. Atomic Absorption and Emission Spectroscopy
b. Molecular fluorescence spectroscopy
c. Flame Photometry
d. I.R. Spectroscopy
e. Mass Spectroscopy
f. NMR Spectroscopy
g. U.V./Visible Spectroscopy
2. CHROMATOGRAPHIC METHODS: Column Chromatography, Thin Layer
Chromatography, Gas Liquid Chromatography, HP LC, LCMS, GC MS, Capillary
Electrophoresis.
3. ELECTRO CHEMICAL METHO DS: Potentiometry, Polarography and
Radiochemical Techniques.
4. THERMAL ANALYSIS: Differential Scanning Calorimetry, Differential Thermal
Analysis, Thermo Gravimetric Analysis .
5. OCCURE NCE, PROPERTIES, PREPARATION AND APPLICATION OF
OFFICIAL INORGANIC COMPOUNDS: Aluminium Hydroxide, Ammonium
Chloride, Sodium Carbonate, Magnesium Carbonate, Lithium Carbonate, Sodium
Nitrite, Calcium Gluconate, Antimony Gluconate, Ferrous Fumarate, Ferrous Sulfate
and Silver Nitrate.
6. TITRIMETRIC ANALYSIS: Acid-basetitration, Oxidation -reduction titration,
Argentometric titration, Complexometric titration, Non -aqueous titration etc.
 PHARMACEUTICAL CHEMISTRY-III (PHARMACEUTICAL ANALYSIS)
(Practical)
Paper 11 Mar ks 100

NOTE:- Practical of the subject shall be designed from time to time on the basis of the above
mentioned theoretical topics and availability of the requirements e.g. Determination
of the Purity and Composition of the unknown drugs by using at least each of the above
techniques. (Note: A minimum of 20 practicals will be conducted ).

SUGGESTED READINGS:

1. Ahuja S, Scypinski S. Handbook of modern pharmaceutical analysis. 2nd Ed.

Academic Press; 2010.
2. Armstrong NA, James KC. Understanding experimental design and

interpretation in pharmaceutics. 1st Ed. Taylor & Francis Publishers; 1990.

3. Beckett AH, Stennlake JB. Practical Pharmaceutical Chemistry. 4th Ed. The
Aulton Press; 2001.

4. Braithwaite A, Smith FJ. Ch romatographic Methods. 5th Ed. Chapman and Hall;
1995.

5. Brittain HG. Spectroscopy of pharmaceutical solids. 1st Ed. Taylor & Francis; 2006.

6. Hamilton R, Sewell PA. Introduction to HPLC. 1st Ed. Chapman & Hall; 1982.

7. Heftmann E. Ch romatography. 6th Ed. Von Nostrond Reinheld Co; 2004.

8. Kazakevich Y, LoBrutto R. HPLC for pharmaceutical scientists. 1st Ed. John Wiley
and Sons; 2007.

9. Kemp W. Organic Spectroscopy. 3rd Ed. Ellsi Horwood; 2008.

10. Knevel AM, Digangi FE. Jenkin’s quantitative Pharmaceutical Ch emistry. 7th Ed.
 McGraw Hill; 1977.

11. 11. Lough WJ, Wainer WI. High Performance Liquid Chromatography. 1st
Ed. Blacki Academic Press; 1995.
12. Moffat AC, Osselton DM, Widdop B. Clarke’s Analysis of Drugs and Poisons.

4th Ed. Pharmaceutical Press; 2011.

13. Pryde A, Gilbert MJ. Applications of High Performance Liquid Chromatograph y.

1st Ed. Chapman & Hall; 1979.

14. Snyder LR, Kirkland JJ, Dolan JW. Introduction to modern liquid chromatography.

3rd Ed. John Wiley & Sons Inc; 2009.

15. Stahl E. Thin Layer Chromatography. 2nd Ed. Berlin: Springer Verlag; 1969.

16. Williams DH, Fleming I. Spectroscopic methods in organic chemistry. 6th Ed.
McGraw Hill; 2007.

PHARMACY PRACTICE -III (COMPUTER AND ITS APPLICATION IN

PHARMACY) (Theory)
Paper 6 Mar ks 50

Course Objective:

In this subject all topics of computer sciences will be taught with special reference to their
Pharmaceutical Applications.

1. FUNDAME NTALS BASIC CONCEPT OF COMPUTERS: History o f Data Processing,

Types of Computers, Components of a Computer, Computer System and Business Computer
System, Backing Storage Devices, Unit of Memory, Viruses and Anti -viruses Issues.
2. RESEARCH METHODOLOGIES:

3. SYSTEM ANALYSIS AND DESIGN: What is a System?, Steps in s ystem life cycle, Data
Gathering and Data Analysis, Designing a New System, Development and Implementation of
New S ystem, Documentation.

4. DATA PROCESSING: Data Processing, The Data Processing Cycle, The Collecti on and
Computing of data, Manual collection of data, The main methods of data input, Devices used to
collect data, Data Verification, Data Validation, Output and Recording of data, Types of data
processing systems, Types of Computer Operation, Batch Processing and Real -time Processing.

5. APPLICATION OF COMPUTERS IN HOSPITAL PHARMACY: Patterns of Computer

use in Hospital Pharmacy, Patient record database management, Medication order entry, Drug
labels and list, Intravenous solution and admixture, Patient Medication profiles, Inventory
control, Management report & Statistics.

6. APPLICATION OF COMPUTER IN COMMUNITY PHARMACY: Computerizing the

Prescription Dispensing process, Use of Computers for Pharmaceutical Care in community
pharmacy, Accounting and General Ledger system.

7. APPLICATION OF DRUG INFORMATION RETRIEVAL & STORAGE: Introduction

Advantages of Computerized Literature Retrieval use of Computerized Retrieval.

8. DATA ANALYSIS: Int roduction and implementations of statistical design and test.
Students T -test, Chi Square, ANOVA using statistical packages like SPSS, M ed Calc, Kinetica
etc.

PARMACY PRACTICE -III (COMPUTER AND ITS APPLICATION IN

PHARMACY) Practical
Paper 12 Mar ks 50
1. INTERNET AND E -MAIL: Internet and Microsoft Internet Explorer 5, Addresses, Links
and Downloading, Searching the Internet, E -mail and Newsgroups, Favourites, security and
Customizing Explorer.

2. WEB PAGE DEVELOPMENT: Introduction to Front -page, Creating a First Web site,
Ba sic Formatting Techniques, Manipulating Tables within Front -page, Front-page, Picture and
MultiMedia, Hyper linking, Bookmarks and Image Maps, Introducing Front -page
―components‖, Front-page and Frames, Managing your Web, Good site design, Publishing and
publicizing.

3. DATA PRESENTATION SKILLS : MS-Word, MS-Excel, MS-Power point.

4. UNDERSTANDING AND APPLICATION OF STATISTICAL PACKAGE S: SPSS,

Kinetica, Med Calc.

SUGGESTED READINGS:

1. Dennis N. Programmer's Guide to MS-DOS. 2nd Ed. BradyGames; 1987.

2. Elias M. System Analysis and design. 2nd Ed. Award Galgotia Publications; 1985.

3. Norton P, Clark S. Peter Norton's Complete Guide to DOS 6.22. 1st Ed. Sams
Publishers; 1994.

4. Norton P, Clark S. Peter Norton's New Inside the PC. 1st Ed. Sams Publishers; 2002.