AI-Powered Cyber Resilience Framework for Hospitals

1. Identify (Risk Management & Asset Visibility)

Define Cyber Resilience Scope
• Identify hospital departments, IoMT devices, EHR systems, and external
networks that fall under the resilience framework.
Asset Inventory & Risk Categorization
• Maintain a real-time asset inventory for IoMT devices, IT infrastructure, AI
systems, and data flow mappings.
• Classify assets based on criticality, data sensitivity, and impact on patient
care.
Threat Intelligence & Risk Assessment
• Use AI-driven threat intelligence platforms to continuously assess threats
against IoMT devices.
• Implement a risk scoring model for IoMT, prioritizing devices based on
exploitability and severity.
Compliance Mapping
• Align AI-powered resilience measures with NIST SP 800-53, 800-171, HIPAA,
and ISO 27001.

2. Protect (Preventive Controls for IoMT & Hospital IT Systems)

AI-Driven Access Control & Authentication
• Implement Zero Trust Architecture (ZTA) for IoMT & IT systems.
• Enforce multi-factor authentication (MFA) & AI-powered anomaly-based
access control.
Secure IoMT Configuration & Hardening
• Apply device segmentation (e.g., VLANs) to isolate IoMT devices from critical
hospital networks.
• Use endpoint security solutions with AI-based intrusion detection for IoMT
devices.
Patch & Firmware Management
• AI-driven predictive patching to automate IoMT firmware updates & vulnerability
remediation.
Data Encryption & Tokenization
• Use AI-enhanced encryption techniques for patient data in transit & at rest.
• Implement data masking & anonymization for IoMT-generated health records.

3. Detect (AI-Driven Threat Monitoring & Anomaly Detection)

AI-Powered Network & Behavioral Monitoring
• Deploy AI-based Security Information and Event Management (SIEM) tools for
real-time threat analytics.
• Use machine learning models to detect anomalous behavior in IoMT
communication patterns.
Automated Threat Intelligence & Correlation
• Integrate AI-driven threat intelligence feeds to correlate IoMT vulnerabilities
with emerging attack patterns.
Continuous Security Posture Assessment
 • Conduct automated red teaming & penetration testing to evaluate IoMT
security posture.

4. Respond (Incident Response & AI-Driven Mitigation)

AI-Enhanced Incident Response (IR) Automation
• Deploy AI playbooks for automated incident triage & response.
• Implement AI-assisted forensic tools for rapid threat investigation in hospital
systems.
Cyber Resilience Orchestration
• Use AI-driven Security Orchestration, Automation, and Response
(SOAR) to contain threats in real time.
• Integrate AI-assisted deception techniques to mislead attackers targeting
IoMT.

5. Recover (AI-Driven Business Continuity & Resilience Testing)

AI-Based Disaster Recovery & Data Integrity Assurance
• Implement AI-enhanced backup & restoration solutions for healthcare IT &
IoMT data.
• Use blockchain-based data integrity validation for tamper-proof patient
records.
Cyber Resilience Simulation & Continuous Learning
• AI-driven cyber resilience tabletop exercises for hospital cybersecurity teams.
• Use reinforcement learning models to enhance incident response
e[ectiveness over time.
Key Deliverables for AI-Powered Cyber Resilience Framework
✅ Risk Assessment Report for IoMT & Hospital IT
✅ AI-Powered Access Control & Authentication Plan
✅ AI-Based Network Monitoring & Threat Detection Strategy
✅ Incident Response Playbooks (AI-Driven)
✅ IoMT Hardening & Secure Configuration Guide
✅ Automated Patching & Threat Intelligence Integration Plan
✅ Recovery & Business Continuity AI Strategy
This document serves as a blueprint for implementing an AI-powered Cyber
Resilience Framework, ensuring hospitals can mitigate IoMT
vulnerabilities and enhance overall cybersecurity.

STEPS IN USING CAIRIS TO IMPROVE FRAMEWORK

1. Threat Modeling for IoMT Devices
• Define assets: IoMT devices, AI-powered threat detection systems, EHR
databases, and hospital IT infrastructure.
• Identify threats: Use CAIRIS to model potential attack vectors such
as unauthorized access, ransomware, supply chain attacks, and insider
threats.
• Use attack trees to visualize how AI-based threats may target hospital systems.
2. Risk Assessment & STRIDE-Based Analysis
• Perform risk assessments on IoMT devices and AI-driven security mechanisms.
• Map risks using STRIDE (Spoofing, Tampering, Repudiation, Information
Disclosure, Denial of Service, Elevation of Privilege).
• Associate risks with mitigation strategies, such as Zero Trust, AI-driven threat
detection, and continuous monitoring.
3. Security Requirements Modeling
• Define security requirements based on NIST SP 800-53, HIPAA, and ISO 27001.
• Model security policies and constraints for AI-driven security operations.
• Generate misuse case diagrams to identify how attackers may exploit hospital
vulnerabilities.
4. Persona & Attack Scenarios
• Create personas for hospital IT teams, cybersecurity analysts, and potential
threat actors (e.g., malicious insiders, cybercriminals).
• Simulate attack scenarios, such as AI model poisoning attacks, IoMT
hijacking, and patient data breaches.
5. Trust Boundary & Data Flow Modeling
• Model trust boundaries between AI-powered systems, IoMT devices, and
hospital networks.
• Use data flow diagrams (DFDs) to visualize how patient data and threat
intelligence are processed, stored, and transmitted.
• Identify weak points in data flows where AI-driven security controls should be
implemented.
6. Security Control Validation
• Validate AI-driven security measures (e.g., intrusion detection, automated
threat intelligence correlation, and predictive patching) against
defined security objectives.
• Generate reports to ensure compliance with hospital cybersecurity standards.