PERCEPTIONS OF THE GRADE 10 STUDENTS OF THE GREAT PLEBEIAN

COLLEGE ON THE EFFECTS OF DENGVAXIA VACCINE

An Undergraduate Thesis Presented to the Faculty of

The College of Teacher Education

The Great Plebeian College

In Partial Fulfillment of the Requirements for the

Degree of Bachelor of Secondary Education

Major in Social Studies

Researchers:

ANGELICA B. SAMELO

CLARISSA V. CABATIC

ROSEMARIE O. ARELLANO

JENALYN P. PETALVER

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 CHAPTER I

THE PROBLEM

This chapter presents the background of the study, statement of the

problem, assumption and significance of the study, scope and delimitation,

objectives of the study and definition of terms.

INTRODUCTION

Background of the Study

Dengue Vaccine is a vaccine to prevent dengue fever in humans. The

World Health Organization only recommends the vaccine as a possible option

in areas of the world where the disease is common.

In 2017 the manufacturer recommended that the vaccine only be used

in people who have previously had a dengue infection, as outcomes may be

worsened in those who have not been previously infected. This has caused a

scandal in the Philippines where more than 733,000 children were vaccinated

regardless of zero status.

The development of vaccine for dengue fever began as early as 1929,

but has been hindered first by incomplete knowledge of the disease

pathogenesis, and later by need to simultaneously create a stable immunity

against all four dengue serotypes.

Several vaccine candidates are in development including live

attenuated, inactivated, DNA and subunit vaccines. Live attenuated vaccine

candidates are the furthest along in development.

In 2016 a partially effective vaccine for dengue fever (Dengvaxia)

became commercially available in 11 countries: Mexico, the Philippines,

Indonesia, Brazil, El Salvador, Costa Rica, Paraguay, Guatamala, Peru,

Thailand and Singapore.

World Health Organization (WHO) recommends that use be limited to

areas where the disease is common because vaccination may actually

increase the risk of dengue fever in people who have not been previously

infected with the dengue virus because of the phenomenon of antibody

dependent enhancement.

CYD- TVD, sold under the brand name Dengvaxia and made by Sanofi

Pasteur, is a live attenuated tetravalent chimeric vaccine made using

recombinant DNA technology by replacing the PrM (pre- membrane) and E

(envelope) structural genes of the yellow fever attenuated 17D strain

vaccine with those from four of the five dengue serotypes.

In 2017 the manufacturer recommended that the vaccine only be used

in people who have previously had a dengue infection as otherwise there

was evidence it may worsen subsequent infections. The initial protocol did

not require baseline blood samples prior to vaccination in order to establish

not been previously exposed.

In November 2017 Sanofi acknowledged that some participants were put at

risk of severe dengue if they had no prior exposure to the infection;

subsequently the Philippines government suspended the mass immunization

program with the backing of the World Health Organization (WHO) began a

review of the safety data.

Statement of the Problem

This study aimed to determine the perceptions of the grade 10

students of the Great Plebeian College of the effects of Dengvaxia

Vaccine.

Specifically, the study attempts to answer the following sub-problems:

1. What is the profile of the Grade 10 students in terms of:

1.1 Age;

1.2 Sex;

1.3 Section;

2. What is the level of awareness of the Grade 10 students on the

dengvaxia vaccine?

3. What are the dangers of the dengvaxia vaccine as perceived by the

4. What are the advantages and disadvantages of dengvaxia vaccine as

perceived by the respondents?

5. What are the problems to be encounter in the implementation of the

dengvaxia vaccine as perceived by the Grade 10 students and their

degree of seriousness?

Objective of the Study

The study aimed to:

1. To determine the profile of the students in terms of age, sex and

section.

2. To determine the level of awareness of the grade 10 students on the

dengvaxia vaccine.

3. To determine the dangers of the dengvaxia vaccine as perceived by the

respondents.

4. To know the advantages and disadvantages of dengvaxia vaccine as

perceived by the respondents.

5. To identify the problems to be encounter in the implementation of the

dengvaxia vaccine as perceived by the grade 10 students and their

degree of seriousness.
Assumptions of the Study

To understand clearly the study, the following assumptions were

formulated:

1. That the students have profile regarding their age, sex and section.

2. That some of the students have different level of awareness on the

dengvaxia vaccine.

3. That the students have different level of perception about the dangers

of the dengvaxia vaccine.

4. That the students will know the advantages and disadvantages of

dengvaxia vaccine.

5. That the students know the problems to be encountered toward the

implementation of the dengvaxia vaccine and their degree of

seriousness.

Significance of the Study

This study may benefit the following:

School Administrators. This study help administrators in giving a better

understanding about the IMPACT OF WORK PLANS IN TEACHERS AT THE

GREAT PLEBEIAN COLLEGE.

CHALLENGES FACED BY THE STUDENT TEACHER DURING PRACTICE

TEACHING IN ELEMENTARY AT THE GREAT PLEBEIAN COLLEGE

will help them understand better the effects of Dengvaxia vaccine. By this

study they would be able to disseminate information about the effects of

Dengvaxia vaccine.

Teacher. This will help them understand the different effect of the

Dengvaxia vaccine as perceived by the students. The teacher should be

more sensitive during discussion to avoid offense to the belief of the

students.

Students. This will help them understand and to be knowledgeable of

strategies used by the World Health Organization(WHO) to enhance the

effects of Dengvaxia vaccine,

the advantages and disadvantages of it.

Parents. This will help them enlighten about the effects of Dengvaxia

vaccine. The parents should be more aware to the feelings of their children

about the sad matter.

Future Researchers. This will serve as basis in conducting a similar study

or research.

Scope and Delimitation of the Study

This study will conduct to determine the perceptions of the grade 10

Academic Year 2018-2019 with a total number of 250 respondents.

Definition of Terms

For clarification, the following terms used in this study were hereby

defined in order to have common understanding to the:

Implementation. Is a noun of the verb implement, or to carry out or

accomplish; use this word to describe the process of turning formal plans

often very detailed.

Perception. The state of being or process of becoming aware of something

through senses.

Perceived. To become aware of something directly through any of the

senses, especially sight or hearing.

Effect. It refers to actual achievement of a final result.

Student. A student enrolled in a school or college; someone who has been

admitted to a school or college.

Dengue. A debilitating viral disease of tropics, transmitted by mosquitoes

and causing sudden fever and acute paints in the joints.

Dengvaxia. Is a vaccine to prevent dengue in humans.

Vaccine. A substance used to stimulate the production of antibodies and

substitute treated to act as an antigen without including the disease.

World Health Organization (WHO). Is a specialized agency of the United

Nations that is concerned with international public health.

Deoxyribonucleic acid (DNA).Is an acid in the chromosomes in the center

of the cells of living things; determines the particular structure and functions

of every cell and is responsible for characteristics being passed on from

parents to their children.