Pain Pathway
Presented by:
Roland E. Mallarez
NEOspinothalimic
tract
Fast-sharp pain
Mechanical/ Thermal
Aδ fibers
6 and 30 m/s
Terminates in brainstem
and thalamus
Easily localized
NT Glutamate
Pain Pathways
Paleo-Spinothalamic
Tract
Slow-chronic pain
Chemical
C fiber
0.5 and 2 m/s
Most pain signals
terminate in
brainstem and few in
thalamus
Poorly localized
NT Substance P
Pain Pathways