Biostartups and Industries in India and Abroad

Biostartups and Industries in India and Abroad

• 1.
  Presented By Sijo A Ph.D.Research Scholar (Microbiology) School of Biosciences, MACFAST College Tiruvalla, Kerala BIOSTARTUPS AND INDUSTRIES
• 2.
  Introduction to Bioentrepreneurshipand Biostartups • Bioentrepreneurship is the process of creating and managing businesses in the biotechnology sector, focusing on translating scientific research into commercial products and services. Key Areas in Bioentrepreneurship: • Healthcare & Pharmaceuticals – Developing novel drugs, vaccines, and diagnostics (e.g., Moderna (U.S) for mRNA vaccines). • Agricultural Biotechnology – GM crops, biofertilizers, and biopesticides (e.g., Monsanto (U.S) for Bt cotton). • Industrial Biotechnology – Enzyme production, biofuels, and biodegradable plastics (e.g., Novozymes (Denmark) for industrial enzymes). • Environmental Biotechnology – Waste treatment, bioremediation, and sustainable solutions (e.g., LanzaTech (U.S) for carbon recycling).
• 3.
  Introduction to Bioentrepreneurshipand Biostartups Stages of a Biostartup: 1. Ideation and Research – Identifying a biotech problem and developing a solution. 2. Business Planning – Preparing a business model, market analysis, and funding strategy. 3. Funding and Investment – Seeking venture capital, grants, or government support. 4. Regulatory Approvals – Ensuring compliance with safety and ethical guidelines (e.g., FDA, EMA approvals). 5. Product Development – Scaling up laboratory research for market production. 6. Commercialization and Scaling – Launching the product, building partnerships, and expanding operations.
• 4.
  Marketing of BiotechnologyProducts • Marketing biotechnology products involves strategies to promote and sell biotech innovations in various sectors, ensuring regulatory compliance and customer trust. Key Strategies for Marketing Biotech Products: 1. Market Research & Segmentation – Identifying target customers, such as healthcare professionals, farmers, or industrial users. 2. Regulatory Compliance – Meeting the legal requirements for biotech products (e.g., FDA, EPA, WHO approvals). 3. Branding and Positioning – Establishing credibility through scientific validation and certifications. 4. Intellectual Property Protection – Patents, trademarks, and licensing agreements to secure innovation (e.g., CRISPR patents by Editas Medicine). 5. Pricing Strategy – Balancing affordability with profitability, considering R&D and production costs. 6. Distribution Channels – Direct sales, partnerships, online platforms, and biotech conferences. 7. Digital Marketing & Public Relations – Using social media, scientific publications, and industry events to create awareness.
• 5.
  Biotechnology Institutes inIndia 1. Indian Institute of Science (IISc), Bangalore • Focus: Biotechnology and interdisciplinary life sciences research. • Example: Research in stem cell therapy and synthetic biology. 2. National Institute of Immunology (NII), New Delhi • Focus: Immunology, vaccine development, and infectious diseases research. • Example: Development of monoclonal antibodies for therapeutics. 3. Centre for Cellular and Molecular Biology (CCMB), Hyderabad • Focus: Molecular biology, genetics, and bioinformatics research. • Example: DNA fingerprinting techniques for forensic applications.
• 6.
  Biotechnology Institutes inIndia 4. Institute of Genomics and Integrative Biology (IGIB), New Delhi • Focus: Human genome sequencing, bioinformatics, and disease research. • Example: Contribution to India's first human genome sequencing project. 5. National Centre for Biological Sciences (NCBS), Bangalore • Focus: Neurobiology, cancer biology, and structural biology. • Example: Research in brain mapping and protein folding disorders. 6. Rajiv Gandhi Centre for Biotechnology (RGCB), Kerala • Focus: Molecular medicine, genetic disorders, and cancer biology. • Example: Development of herbal-based anticancer drugs. 7. Biotechnology Industry Research Assistance Council (BIRAC) • Focus: Funding and promoting biotech startups in India. • Example: Providing grants for COVID-19 vaccine development.
• 7.
  Major Biotechnology Companiesin India 1. Biocon Limited (Bangalore) • Focus: Biopharmaceuticals, biosimilars, and biologics. • Example: Development of insulin and monoclonal antibodies for cancer treatment. 2. Serum Institute of India (Pune) • Focus: Vaccine production and immunization programs. • Example: Manufacturing of Covishield (Oxford-AstraZeneca COVID-19 vaccine). 3. Panacea Biotec (New Delhi) • Focus: Vaccines, pharmaceuticals, and biologics. • Example: Development of oral polio vaccines and Hepatitis B vaccines. 4. Dr. Reddy’s Laboratories (Hyderabad) • Focus: Pharmaceutical and biotechnology-based drug development. • Example: Generic biologics and biosimilar drug production.
• 8.
  Major Biotechnology Companiesin India 5. Shantha Biotechnics (Hyderabad) • Focus: Recombinant DNA vaccines and therapeutic proteins. • Example: Development of Shanvac-B, India’s first recombinant Hepatitis B vaccine. 6. Zydus Lifesciences (Zydus Cadila) (Ahmedabad) • Focus: Biologics, vaccines, and gene therapy research. • Example: Development of ZyCoV-D, India’s first DNA-based COVID-19 vaccine. 7. Reliance Life Sciences (Mumbai) • Focus: Stem cell therapy, biopharmaceuticals, and molecular diagnostics. • Example: Development of biosimilars and personalized medicine. 8. Bharat Biotech (Hyderabad) • Focus: Vaccines and biotherapeutics. • Example: Development of Covaxin, India’s indigenous COVID-19 vaccine.