This document provides an overview of brain-based learning and teaching. It begins by acknowledging that brain science is continually evolving and outlines some key principles of brain-based learning, including that it is student-centered, focuses on how learning makes students feel, and occurs best when students are enthusiastic and not stressed. It then discusses various parts of the brain and their functions, how the brain determines importance through emotion and attention, and outlines twelve principles of brain-based teaching related to how the brain processes information in parallel, engages the entire body, develops uniquely, perceives wholes and parts simultaneously, involves conscious and unconscious processes, searches for meaning, is impacted by emotions, learns through appropriate challenge, patterns information, organizes memory in different