Lean is a manufacturing production approach that focuses on precisely defining value, defining the value stream, making value flow through the process, and pulling value rather than pushing it. Agile is a software development movement driven by collaboration with customers to deliver value through frequent changes. Key takeaways are to grow a repeatable yet adaptable process, deliver in small batches, pivot when conditions change, address bottlenecks, understand lean and agile principles versus methodologies, and watch out for saboteurs like unengaged stakeholders.