The document provides 14 tips for optimizing Python code for speed. It recommends profiling code with %timeit and %prun in IPython, using iterators and generators when possible, using list comprehensions over for loops, xrange over range, map, filter and reduce, minimizing function calls and global variables, using threads for I/O-bound processes, and using the C versions of Python libraries when performance is critical. It also provides links to additional resources on Python optimization.