The document discusses how to run applications on Amazon EC2. It covers choosing a region and availability zone, defining the architecture, selecting instance types, bootstrapping and configuring instances, deploying applications, and scaling. Key points include using Chef for configuration management, deploying with Capistrano hooks, and addressing issues with idempotency and documentation. The goal is to set up a browser game with 1.2 million daily users on over 130 EC2 instances to handle 120,000 requests per minute.